The Mark O. Hatfield United States Courthouse is a federal courthouse in Portland, Oregon. It is named in honor of former U.S. Senator Mark O. Hatfield and is used by the United States District Court for the District of Oregon.

With 16 stories, the courthouse rises to a height of 318 feet (97 m), making it the tenth-tallest building in Portland. The building contains approximately 563,000 square feet.